Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (181 aa)    
Predicted Functional Partners:
supt20h
SPT20 homolog, SAGA complex component.
    
 0.986
tada2b
Transcriptional adapter.
    
 0.986
tada3
Transcriptional adaptor 3 (NGG1 homolog, yeast)-like.
    
 0.985
sgf29
SAGA complex associated factor 29.
    
 0.984
trrap
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.984
taf10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.983
supt7l
SPT7 like, STAGA complex gamma subunit.
    
 0.981
taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor.
    
 0.981
supt3h
SPT3 homolog, SAGA and STAGA complex component.
    
 0.979
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 0.978
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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