Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
map3k21Mitogen-activated protein kinase kinase kinase. (1040 aa)    
Predicted Functional Partners:
I3KP91_ORENI
Mitogen-activated protein kinase kinase 7.
   
 0.957
map3k10
Mitogen-activated protein kinase kinase kinase 10.
     
  0.916
map3k9
Mitogen-activated protein kinase kinase kinase.
     
  0.916
cdc42
Cell division cycle 42.
    
 0.795
htt
Huntingtin.
   
 0.685
LOC100690324
Mitogen-activated protein kinase 8 interacting protein 1.
    
 0.664
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.639
tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
   
 0.637
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 0.634
mapk8ip2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 0.634
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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