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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3IWR9_ORENIUncharacterized protein. (704 aa)    
Predicted Functional Partners:
cog8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.653
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 
 0.612
twf1
Twinfilin actin-binding protein 1a.
   
 0.579
cog3
Component of oligomeric golgi complex 3.
    
 
 0.550
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
  0.504
LOC100693503
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
  0.504
cog4
Component of oligomeric golgi complex 4.
    
 
 0.484
mpp1
Membrane protein, palmitoylated 1; Belongs to the MAGUK family.
    
  0.484
Smim7
Small integral membrane protein 7.
    
 
 0.484
LOC100711937
WASP like actin nucleation promoting factor a.
    
 
 0.474
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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