STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plcd3Phosphoinositide phospholipase C. (791 aa)    
Predicted Functional Partners:
LOC100692694
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 
 0.909
Itpr3
Inositol 1,4,5-trisphosphate receptor, type 3.
   
 
 0.909
I3KSK9_ORENI
Inositol 1,4,5-trisphosphate receptor, type 1a.
   
 
 0.909
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.908
pikfyve
Phosphoinositide kinase, FYVE finger containing.
     
 0.901
Mtm1
Myotubularin 1.
     
 0.901
inpp1
Si:ch211-160o17.2.
     
 0.900
LOC100700292
Uncharacterized protein; Belongs to the histidine acid phosphatase family.
     
  0.900
plce1
Phospholipase C, epsilon 1.
     
 
0.784
Plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
0.755
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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