Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100705127Homeobox domain-containing protein. (295 aa)    
Predicted Functional Partners:
Gbx2
Gastrulation brain homeobox 2.
    
 0.687
LOC100704522
Zinc finger protein 366.
   
 
 0.640
otx1
Homeobox domain-containing protein.
   
  
 0.596
LOC100712246
Orthodenticle homeobox 1.
   
  
 0.596
fgf5
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.573
LOC100691488
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.572
I3KZS2_ORENI
SRY-box transcription factor 2.
   
 0.562
LOC100706011
POU domain protein.
   
 0.561
LOC100698401
Homeobox B4a.
     
 0.552
hhex
Homeobox domain-containing protein.
   
  
 0.538
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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