Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
actr10Actin related protein 10; Belongs to the actin family. (417 aa)    
Predicted Functional Partners:
dctn5
Dynactin 5.
    
 0.999
dctn2
Dynactin 2 (p50).
   
 0.999
dctn4
Dynactin 4.
   
 0.998
DCTN6
Dynactin subunit 6.
   
 0.996
dctn3
Dynactin 3 (p22).
   
 0.996
LOC100690576
Uncharacterized protein.
   
 0.996
LOC100691670
Actin related protein 1, centractin.
   
 0.995
LOC100689885
CAP-Gly domain-containing protein.
    
 0.990
I3KU39_ORENI
Dynactin 1b.
    
 0.990
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.941
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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