Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YY1YY1 transcription factor b. (367 aa)    
Predicted Functional Partners:
LOC100703461
YY1 transcription factor.
  
  
 
0.959
nfrkb
Nuclear factor related to kappaB binding protein.
    
 0.923
ino80c
INO80 complex subunit C.
    
 0.923
actr5
Actin related protein 5; Belongs to the actin family.
    
 0.919
actr8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.918
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.916
ino80
INO80 complex ATPase subunit.
   
  0.914
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.913
ezh2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.913
ino80e
INO80 complex subunit E.
    
  0.904
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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