abcg8 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

abcg8

ATP-binding cassette, sub-family G (WHITE), member 8. (668 aa)

Predicted Functional Partners:

abcg5

0.999

LOC100709377

0.675

LOC100697646

0.675

tspan3

0.664

TSPAN3

0.664

nr1h3

0.662

LOC100702067

0.660

LOC100700332

0.660

I3K981_ORENI

0.646

kcnk5

0.619

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3K981_ORENI	LOC100697646	ENSONIP00000039897	ENSONIP00000049566	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.555
I3K981_ORENI	abcg5	ENSONIP00000039897	ENSONIP00000001153	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.660
I3K981_ORENI	abcg8	ENSONIP00000039897	ENSONIP00000001157	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.646
LOC100697646	I3K981_ORENI	ENSONIP00000049566	ENSONIP00000039897	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	0.555
LOC100697646	LOC100700332	ENSONIP00000049566	ENSONIP00000035775	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Xenotropic and polytropic retrovirus receptor 1b.	0.440
LOC100697646	LOC100702067	ENSONIP00000049566	ENSONIP00000002386	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Xenotropic and polytropic retrovirus receptor 1a.	0.440
LOC100697646	LOC100709377	ENSONIP00000049566	ENSONIP00000041817	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.806
LOC100697646	abcg5	ENSONIP00000049566	ENSONIP00000001153	3-hydroxy-3-methylglutaryl coenzyme A reductase.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.734
LOC100697646	abcg8	ENSONIP00000049566	ENSONIP00000001157	3-hydroxy-3-methylglutaryl coenzyme A reductase.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.675
LOC100697646	nr1h3	ENSONIP00000049566	ENSONIP00000007341	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Nuclear receptor subfamily 1, group H, member 3.	0.609
LOC100700332	LOC100697646	ENSONIP00000035775	ENSONIP00000049566	Xenotropic and polytropic retrovirus receptor 1b.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.440
LOC100700332	LOC100709377	ENSONIP00000035775	ENSONIP00000041817	Xenotropic and polytropic retrovirus receptor 1b.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.451
LOC100700332	abcg5	ENSONIP00000035775	ENSONIP00000001153	Xenotropic and polytropic retrovirus receptor 1b.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.667
LOC100700332	abcg8	ENSONIP00000035775	ENSONIP00000001157	Xenotropic and polytropic retrovirus receptor 1b.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.660
LOC100700332	nr1h3	ENSONIP00000035775	ENSONIP00000007341	Xenotropic and polytropic retrovirus receptor 1b.	Nuclear receptor subfamily 1, group H, member 3.	0.451
LOC100702067	LOC100697646	ENSONIP00000002386	ENSONIP00000049566	Xenotropic and polytropic retrovirus receptor 1a.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.440
LOC100702067	LOC100709377	ENSONIP00000002386	ENSONIP00000041817	Xenotropic and polytropic retrovirus receptor 1a.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.451
LOC100702067	abcg5	ENSONIP00000002386	ENSONIP00000001153	Xenotropic and polytropic retrovirus receptor 1a.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.667
LOC100702067	abcg8	ENSONIP00000002386	ENSONIP00000001157	Xenotropic and polytropic retrovirus receptor 1a.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.660
LOC100702067	nr1h3	ENSONIP00000002386	ENSONIP00000007341	Xenotropic and polytropic retrovirus receptor 1a.	Nuclear receptor subfamily 1, group H, member 3.	0.451