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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abcg8ATP-binding cassette, sub-family G (WHITE), member 8. (668 aa)    
Predicted Functional Partners:
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5.
  
0.999
LOC100694446
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.709
LOC100697646
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.596
dhcr7
7-dehydrocholesterol reductase.
   
  
 0.572
LOC100709377
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.544
atp5f1c
ATP synthase subunit gamma.
   
   0.538
cdca8
Cell division cycle associated 8.
   
 
 0.530
LOC100708634
Apolipoprotein A-Ib.
   
 0.530
nr1h3
Nuclear receptor subfamily 1, group H, member 3.
   
 0.528
atp5f1d
ATP synthase F1 subunit delta.
   
   0.526
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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