Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slc19a1Solute carrier family 19 member 1. (531 aa)    
Predicted Functional Partners:
LOC100707189
Uncharacterized protein.
      
 0.762
ENSONIP00000078563
annotation not available
    
   0.759
hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase.
      
 0.754
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
      
 0.692
slc25a19
Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.675
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
      
 0.660
Msh4
MutS homolog 4.
      
 0.641
slc25a26
Solute carrier family 25 member 26; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.636
hmgcll1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.
      
 0.627
slc46a2
Solute carrier family 46 member 2.
      
 0.620
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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