Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3IX36_ORENICodanin 1. (893 aa)    
Predicted Functional Partners:
lg19h15orf41
Uncharacterized protein C15orf41 homolog isoform X1.
    
 
 0.931
LOC100711821
Anti-silencing function 1Ba histone chaperone.
    
 
 0.885
LOC100702465
Histone chaperone asf1b-B.
    
 
 0.885
I3KE98_ORENI
Zwilch kinetochore protein.
      
 0.811
Wdfy3
WD repeat and FYVE domain containing 3.
      
 0.806
eps15l1
Epidermal growth factor receptor pathway substrate 15-like 1a.
      
 0.778
hps5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
      
 0.705
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.673
il13ra2
Interleukin 13 receptor, alpha 2.
      
 0.667
mecr
Mitochondrial trans-2-enoyl-CoA reductase.
    
 
 0.661
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (10%) [HD]