STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1239 aa)    
Predicted Functional Partners:
LOC100697949
Uncharacterized protein.
    
 0.960
LOC100709052
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.960
LOC100706405
Uncharacterized protein.
    
 0.956
LOC100692694
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 0.922
Itpr3
Inositol 1,4,5-trisphosphate receptor, type 3.
   
 0.922
I3KSK9_ORENI
Inositol 1,4,5-trisphosphate receptor, type 1a.
   
 0.922
I3IW02_ORENI
G protein-coupled receptor, class C, group 6, member A.
     
 0.913
casr
Calcium-sensing receptor.
     
 0.913
ENSONIP00000066252
G-protein coupled receptor family C group 6 member A-like.
     
 0.913
inpp1
Si:ch211-160o17.2.
     
 0.908
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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