Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
six2SIX homeobox 2a. (290 aa)    
Predicted Functional Partners:
eya3
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.681
eya4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.680
eya1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.680
eya2
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.680
LOC100703352
RAB8A, member RAS oncogene family.
   
  
 0.564
rab8a
RAB8A, member RAS oncogene family.
   
  
 0.564
rab27b
RAB27B, member RAS oncogene family.
      
 0.562
rps6ka3
Ribosomal protein S6 kinase.
      
 0.561
LOC106096430
RAB19, member RAS oncogene family.
      
 0.556
RAB9A
RAB9A, member RAS oncogene family.
      
 0.555
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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