Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
LOC100700804Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (412 aa)    
Predicted Functional Partners:
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.712
ENSONIP00000051556
Uncharacterized protein LOC102079195.
   
 0.707
ENSONIP00000057536
Gamma-glutamyltranspeptidase / glutathione hydrolase.
     
  0.599
LOC100694858
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
   
 
 0.595
chac2
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.580
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
     
 0.566
txndc12
Thioredoxin domain containing 12 (endoplasmic reticulum).
   
 
  0.566
mgst2
Microsomal glutathione S-transferase 2.
     
  0.555
LOC100694673
Microsomal glutathione S-transferase 1.2.
     
 0.549
LOC100699992
Uncharacterized protein.
   
 
 0.545
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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