Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spon2Spondin 2b, extracellular matrix protein. (338 aa)    
Predicted Functional Partners:
gnl2
Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
      
 0.924
slc38a10
Solute carrier family 38 member 10.
      
 0.884
RAB28
RAB28, member RAS oncogene family.
      
 0.879
fam163b
Family with sequence similarity 163 member B, genome duplicate a.
      
 0.876
neto1
Neuropilin (NRP) and tolloid (TLL)-like 1, like.
      
 0.856
LOC100690409
Neuropilin (NRP) and tolloid (TLL)-like 1.
      
 0.856
lmf1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
   
  
 0.855
I3KTW5_ORENI
NRDE-2, necessary for RNA interference, domain containing.
      
 0.824
chchd7
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 isoform X2.
      
 0.768
nudt7
Nudix (nucleoside diphosphate linked moiety X)-type motif 7.
      
 0.726
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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