Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irak1bp1Interleukin-1 receptor-associated kinase 1 binding protein 1. (247 aa)    
Predicted Functional Partners:
ccnc
Cyclin C; Belongs to the cyclin family.
      
 0.815
LOC100702124
Interleukin 1 receptor type 2.
      
 0.747
Ibtk
Inhibitor of Bruton agammaglobulinemia tyrosine kinase.
      
 0.746
LOC102079252
Si:ch211-207e14.4.
      
 0.677
il17rd
Interleukin 17 receptor D.
      
 0.677
cdk20
Cyclin-dependent kinase 20.
      
 0.638
amdhd1
Amidohydrolase domain containing 1.
      
 0.629
Acot8
Acyl-CoA thioesterase 8.
      
 0.619
ppp1r7
Protein phosphatase 1, regulatory (inhibitor) subunit 7.
      
 0.614
acss3
Acyl-CoA synthetase short chain family member 3.
      
 0.610
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.