Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100702161T-box transcription factor 18. (512 aa)    
Predicted Functional Partners:
tcf21
Basic helix-loop-helix protein 21.
     
 0.911
shox2
Short stature homeobox 2.
   
 0.766
cep162
Centrosomal protein 162.
      
 0.708
CDH20
Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.707
LOC100697378
Sine oculis binding protein homolog (Drosophila) b.
      
 0.706
CDH6
Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.704
NT5E
5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.
      
 0.702
I3KR69_ORENI
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
      
 0.702
gata4
GATA binding protein 4.
   
 0.690
nkx2-5
NK2 homeobox 5.
    
 0.680
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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