Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxo5F-box protein 5. (432 aa)    
Predicted Functional Partners:
cdc27
Cell division cycle 27.
    
 0.984
Anapc2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
 0.965
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.958
I3KQQ3_ORENI
Fizzy/cell division cycle 20 related 1b.
   
 0.956
anapc10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.945
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 0.939
LOC100703880
F-box and WD repeat domain containing 11a.
    
 0.935
cdc20
Cell division cycle 20 homolog.
   
 0.930
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.930
ENSONIP00000057827
Cell division cycle protein 20 homolog B isoform X1.
   
 0.930
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.