STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egfEpidermal growth factor. (1169 aa)    
Predicted Functional Partners:
LOC100711613
Receptor protein-tyrosine kinase.
   
 0.988
egfr
Receptor protein-tyrosine kinase.
   
 0.985
LOC100690421
Receptor protein-tyrosine kinase.
   
 0.961
LOC100709873
Receptor protein-tyrosine kinase.
   
 0.932
LOC100707819
Erb-b2 receptor tyrosine kinase 3b.
   
 0.932
LOC100701577
Receptor protein-tyrosine kinase.
   
 0.932
LOC100712331
Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.
    
 0.921
LOC100690958
Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.
     
 0.914
Pdgfa
Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.
     
 0.914
pdgfd
Platelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family.
    
 0.911
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.