Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100708247Uncharacterized protein. (107 aa)    
Predicted Functional Partners:
LOC100711605
Malate synthase-like.
  
 
 0.946
LOC100712075
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.926
eci2
Enoyl-CoA delta isomerase 2.
  
 0.919
hadh
Uncharacterized protein.
  
 0.855
Cryl1
Crystallin, lambda 1.
  
 0.830
hsdl2
Hydroxysteroid dehydrogenase like 2.
  
 0.830
LOC100698399
Non-specific lipid-transfer protein.
  
 0.806
LOC100711328
Sterol carrier protein 2a; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.806
etfa
Electron transfer flavoprotein subunit alpha.
  
 0.715
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.712
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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