tshr protein (Oreochromis niloticus) - STRING interaction network

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tshr

Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (787 aa)

Predicted Functional Partners:

fshb

0.892

LOC100534501

0.809

LOC100534562

0.796

TSHB

0.796

gpha2

0.730

gphb5

0.725

LOC100707302

0.725

gnb4

0.701

LOC100692028

0.701

crh

0.695

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100534501	fshb	ENSONIP00000029151	ENSONIP00000007338	Luteinizing hormone, beta polypeptide.	FSH beta subunit.	0.778
LOC100534501	tshr	ENSONIP00000029151	ENSONIP00000001448	Luteinizing hormone, beta polypeptide.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.809
LOC100534562	LOC100692028	ENSONIP00000031482	ENSONIP00000005292	Thyrotropin subunit beta.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.476
LOC100534562	TSHB	ENSONIP00000031482	ENSONIP00000074996	Thyrotropin subunit beta.	Thyroid stimulating hormone subunit beta.	0.916
LOC100534562	fshb	ENSONIP00000031482	ENSONIP00000007338	Thyrotropin subunit beta.	FSH beta subunit.	0.961
LOC100534562	gnb4	ENSONIP00000031482	ENSONIP00000002092	Thyrotropin subunit beta.	Guanine nucleotide binding protein (G protein), beta polypeptide 4b.	0.476
LOC100534562	gpha2	ENSONIP00000031482	ENSONIP00000017013	Thyrotropin subunit beta.	Glycoprotein hormone subunit alpha 2.	0.672
LOC100534562	gphb5	ENSONIP00000031482	ENSONIP00000002188	Thyrotropin subunit beta.	Glycoprotein hormone subunit beta 5.	0.415
LOC100534562	tshr	ENSONIP00000031482	ENSONIP00000001448	Thyrotropin subunit beta.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.796
LOC100692028	LOC100534562	ENSONIP00000005292	ENSONIP00000031482	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	Thyrotropin subunit beta.	0.476
LOC100692028	TSHB	ENSONIP00000005292	ENSONIP00000074996	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	Thyroid stimulating hormone subunit beta.	0.476
LOC100692028	crh	ENSONIP00000005292	ENSONIP00000025725	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	Corticotropin releasing hormone b.	0.502
LOC100692028	fshb	ENSONIP00000005292	ENSONIP00000007338	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	FSH beta subunit.	0.426
LOC100692028	tshr	ENSONIP00000005292	ENSONIP00000001448	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.701
LOC100707302	gpha2	ENSONIP00000017014	ENSONIP00000017013	Si:dkey-23i12.9.	Glycoprotein hormone subunit alpha 2.	0.971
LOC100707302	gphb5	ENSONIP00000017014	ENSONIP00000002188	Si:dkey-23i12.9.	Glycoprotein hormone subunit beta 5.	0.916
LOC100707302	tshr	ENSONIP00000017014	ENSONIP00000001448	Si:dkey-23i12.9.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.725
TSHB	LOC100534562	ENSONIP00000074996	ENSONIP00000031482	Thyroid stimulating hormone subunit beta.	Thyrotropin subunit beta.	0.916
TSHB	LOC100692028	ENSONIP00000074996	ENSONIP00000005292	Thyroid stimulating hormone subunit beta.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.476
TSHB	crh	ENSONIP00000074996	ENSONIP00000025725	Thyroid stimulating hormone subunit beta.	Corticotropin releasing hormone b.	0.520

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