Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100694875Zgc:162872. (701 aa)    
Predicted Functional Partners:
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 0.699
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
   
 0.699
arfgap1
ADP-ribosylation factor GTPase activating protein 1.
    
 0.612
ENSONIP00000026111
ADP-ribosylation factor 6b.
    
 0.551
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
      
 0.519
LOC100691828
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
     
 0.497
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.484
arfgap3
ADP-ribosylation factor GTPase activating protein 3.
    
 0.463
arfgap2
ADP-ribosylation factor GTPase activating protein 2.
    
 0.463
LOC100703328
Si:dkey-16l2.16.
    
 
 0.455
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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