Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thumpd2THUMP domain containing 2. (621 aa)    
Predicted Functional Partners:
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
      
 0.727
LOC100692760
Protein DEK isoform X2.
      
 0.699
zbtb8os
Zinc finger and BTB domain containing 8 opposite strand.
      
 0.681
scaf4
SR-related CTD-associated factor 4a.
      
 0.678
ENSONIP00000037750
annotation not available
      
 0.677
trmt11
tRNA methyltransferase 11 homolog.
     
 0.658
Mdn1
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
      
 0.647
mrpl30
Mitochondrial ribosomal protein L30.
      
 0.631
extl2
Exostosin-like glycosyltransferase 2.
      
 0.629
Tprkb
Tp53rk binding protein; Belongs to the CGI121/TPRKB family.
      
 0.628
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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