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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddx43DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. (687 aa)    
Predicted Functional Partners:
slc17a5
Solute carrier family 17 member 5.
    
 
 0.636
LOC100708763
Potassium voltage-gated channel, KQT-like subfamily, member 5a; Belongs to the potassium channel family.
 
  
 
 0.633
LOC100711684
Potassium voltage-gated channel, KQT-like subfamily, member 5b; Belongs to the potassium channel family.
 
  
 
 0.633
sf3b1
Splicing factor 3b, subunit 1.
   
 0.627
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.605
magoh
Mago homolog, exon junction complex subunit.
    
 0.603
LOC100692890
RAN binding protein 2.
  
 0.599
RIMS1
Regulating synaptic membrane exocytosis 1.
      
 0.599
sf3b3
Splicing factor 3b, subunit 3.
   
 0.588
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.587
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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