Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ddx43DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. (687 aa)    
Predicted Functional Partners:
LOC100708763
Potassium voltage-gated channel, KQT-like subfamily, member 5a; Belongs to the potassium channel family.
    
 
 0.697
LOC100711684
Potassium voltage-gated channel, KQT-like subfamily, member 5b; Belongs to the potassium channel family.
    
 
 0.697
srgap2
SLIT-ROBO Rho GTPase activating protein 2.
   
  
 0.656
rxylt1
Ribitol xylosyltransferase 1.
   
  
 0.625
RIMS1
Regulating synaptic membrane exocytosis 1.
      
 0.604
slc17a5
Solute carrier family 17 member 5.
    
 
 0.600
pus7l
Pseudouridine synthase 7 like.
   
 
 0.590
LOC100697195
Cyclin-dependent kinase 11B.
     
 0.581
dhx29
ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.
    
 0.572
srp72
Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.
   
 
 0.557
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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