close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glrx5Glutaredoxin 5 homolog (S. cerevisiae). (156 aa)    
Predicted Functional Partners:
Bola1
BolA family member 1; Belongs to the BolA/IbaG family.
    
 
 0.871
isca1
Iron-sulfur cluster assembly 1 homolog, mitochondrial.
   
 
 0.810
isca2
Iron-sulfur cluster assembly 2.
    
 0.797
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7.
    
 
 0.681
prkrip1
PRKR interacting protein 1.
      
 0.677
LOC100706723
SERPIN domain-containing protein; Belongs to the serpin family.
    
 0.674
nfs1
NFS1 cysteine desulfurase.
    
 
 0.667
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
  
 0.655
hscb
Si:ch211-207k7.4.
    
 0.619
glrx
Glutaredoxin (thioltransferase).
      
 0.589
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: medium (42%) [HD]