ppp3r1 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ppp3r1

WD repeat-containing protein 92. (598 aa)

Predicted Functional Partners:

rpap3

0.991

uxt

0.986

pih1d1

0.985

pfdn2

0.978

uri1

0.975

ruvbl2

0.966

I3IY44_ORENI

0.965

POLR2E

0.949

ruvbl1

0.930

polr3e

0.922

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3IY44_ORENI	ppp3r1	ENSONIP00000064790	ENSONIP00000001534	WD repeat domain 92.	WD repeat-containing protein 92.	0.965
POLR2E	pfdn2	ENSONIP00000036615	ENSONIP00000075419	RNA polymerase II subunit E.	Prefoldin subunit 2.	0.990
POLR2E	pih1d1	ENSONIP00000036615	ENSONIP00000057276	RNA polymerase II subunit E.	PIH1 domain containing 1.	0.979
POLR2E	polr3e	ENSONIP00000036615	ENSONIP00000019938	RNA polymerase II subunit E.	Polymerase (RNA) III (DNA directed) polypeptide E.	0.996
POLR2E	ppp3r1	ENSONIP00000036615	ENSONIP00000001534	RNA polymerase II subunit E.	WD repeat-containing protein 92.	0.949
POLR2E	rpap3	ENSONIP00000036615	ENSONIP00000012499	RNA polymerase II subunit E.	RNA polymerase II associated protein 3.	0.984
POLR2E	ruvbl1	ENSONIP00000036615	ENSONIP00000023970	RNA polymerase II subunit E.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.907
POLR2E	ruvbl2	ENSONIP00000036615	ENSONIP00000049031	RNA polymerase II subunit E.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.913
POLR2E	uri1	ENSONIP00000036615	ENSONIP00000013098	RNA polymerase II subunit E.	URI1 prefoldin like chaperone.	0.991
POLR2E	uxt	ENSONIP00000036615	ENSONIP00000077082	RNA polymerase II subunit E.	Ubiquitously-expressed, prefoldin-like chaperone.	0.981
pfdn2	POLR2E	ENSONIP00000075419	ENSONIP00000036615	Prefoldin subunit 2.	RNA polymerase II subunit E.	0.990
pfdn2	pih1d1	ENSONIP00000075419	ENSONIP00000057276	Prefoldin subunit 2.	PIH1 domain containing 1.	0.967
pfdn2	ppp3r1	ENSONIP00000075419	ENSONIP00000001534	Prefoldin subunit 2.	WD repeat-containing protein 92.	0.978
pfdn2	rpap3	ENSONIP00000075419	ENSONIP00000012499	Prefoldin subunit 2.	RNA polymerase II associated protein 3.	0.984
pfdn2	ruvbl1	ENSONIP00000075419	ENSONIP00000023970	Prefoldin subunit 2.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.916
pfdn2	ruvbl2	ENSONIP00000075419	ENSONIP00000049031	Prefoldin subunit 2.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.964
pfdn2	uri1	ENSONIP00000075419	ENSONIP00000013098	Prefoldin subunit 2.	URI1 prefoldin like chaperone.	0.991
pfdn2	uxt	ENSONIP00000075419	ENSONIP00000077082	Prefoldin subunit 2.	Ubiquitously-expressed, prefoldin-like chaperone.	0.988
pih1d1	POLR2E	ENSONIP00000057276	ENSONIP00000036615	PIH1 domain containing 1.	RNA polymerase II subunit E.	0.979
pih1d1	pfdn2	ENSONIP00000057276	ENSONIP00000075419	PIH1 domain containing 1.	Prefoldin subunit 2.	0.967