PLEKHH3 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

PLEKHH3

Pleckstrin homology, MyTH4 and FERM domain containing H3. (708 aa)

Predicted Functional Partners:

ush1c

0.656

LOC100701022

0.642

I3K581_ORENI

0.631

LOC100690328

0.631

LOC100710621

0.606

myo1c

0.582

myo1b

0.527

LOC100696636

0.519

anks4b

0.519

LOC100698861

0.519

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3K581_ORENI	LOC100690328	ENSONIP00000016276	ENSONIP00000037413	Whirlin a.	Whirlin isoform X1.	0.555
I3K581_ORENI	LOC100696636	ENSONIP00000016276	ENSONIP00000006727	Whirlin a.	Usher syndrome 1Ga (autosomal recessive).	0.503
I3K581_ORENI	LOC100698861	ENSONIP00000016276	ENSONIP00000079986	Whirlin a.	Usher syndrome 1Gb (autosomal recessive).	0.503
I3K581_ORENI	PLEKHH3	ENSONIP00000016276	ENSONIP00000001570	Whirlin a.	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.631
I3K581_ORENI	anks4b	ENSONIP00000016276	ENSONIP00000021614	Whirlin a.	Ankyrin repeat and sterile alpha motif domain containing 4B.	0.503
I3K581_ORENI	ush1c	ENSONIP00000016276	ENSONIP00000062032	Whirlin a.	USH1 protein network component harmonin.	0.761
LOC100690328	I3K581_ORENI	ENSONIP00000037413	ENSONIP00000016276	Whirlin isoform X1.	Whirlin a.	0.555
LOC100690328	LOC100696636	ENSONIP00000037413	ENSONIP00000006727	Whirlin isoform X1.	Usher syndrome 1Ga (autosomal recessive).	0.503
LOC100690328	LOC100698861	ENSONIP00000037413	ENSONIP00000079986	Whirlin isoform X1.	Usher syndrome 1Gb (autosomal recessive).	0.503
LOC100690328	PLEKHH3	ENSONIP00000037413	ENSONIP00000001570	Whirlin isoform X1.	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.631
LOC100690328	anks4b	ENSONIP00000037413	ENSONIP00000021614	Whirlin isoform X1.	Ankyrin repeat and sterile alpha motif domain containing 4B.	0.503
LOC100690328	ush1c	ENSONIP00000037413	ENSONIP00000062032	Whirlin isoform X1.	USH1 protein network component harmonin.	0.761
LOC100696636	I3K581_ORENI	ENSONIP00000006727	ENSONIP00000016276	Usher syndrome 1Ga (autosomal recessive).	Whirlin a.	0.503
LOC100696636	LOC100690328	ENSONIP00000006727	ENSONIP00000037413	Usher syndrome 1Ga (autosomal recessive).	Whirlin isoform X1.	0.503
LOC100696636	PLEKHH3	ENSONIP00000006727	ENSONIP00000001570	Usher syndrome 1Ga (autosomal recessive).	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.519
LOC100696636	ush1c	ENSONIP00000006727	ENSONIP00000062032	Usher syndrome 1Ga (autosomal recessive).	USH1 protein network component harmonin.	0.958
LOC100698861	I3K581_ORENI	ENSONIP00000079986	ENSONIP00000016276	Usher syndrome 1Gb (autosomal recessive).	Whirlin a.	0.503
LOC100698861	LOC100690328	ENSONIP00000079986	ENSONIP00000037413	Usher syndrome 1Gb (autosomal recessive).	Whirlin isoform X1.	0.503
LOC100698861	PLEKHH3	ENSONIP00000079986	ENSONIP00000001570	Usher syndrome 1Gb (autosomal recessive).	Pleckstrin homology, MyTH4 and FERM domain containing H3.	0.519
LOC100698861	ush1c	ENSONIP00000079986	ENSONIP00000062032	Usher syndrome 1Gb (autosomal recessive).	USH1 protein network component harmonin.	0.958