Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100691618Collagen, type X, alpha 1a. (645 aa)    
Predicted Functional Partners:
I3KIR3_ORENI
LAM_G_DOMAIN domain-containing protein.
 
  
  0.849
sp7
Sp7 transcription factor.
    
 0.756
runx2
Runt-related transcription factor.
    
 0.586
I3KM92_ORENI
ZnMc domain-containing protein.
   
 0.580
LOC100711125
ZnMc domain-containing protein.
   
 0.580
I3KEZ4_ORENI
Collagen, type VI, alpha 1.
  
0.570
LOC100702982
Parathyroid hormone-like hormone b.
      
 0.493
LOC100706920
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.492
sox5
SRY-box transcription factor 5.
    
 
 0.476
LOC100703074
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.468
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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