Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100709960Mannosidase, endo-alpha. (440 aa)    
Predicted Functional Partners:
LOC100710823
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.746
ENSONIP00000016918
Adenylate kinase 9.
   
 0.731
gmps
Guanine monophosphate synthase.
  
 
 0.696
I3JR68_ORENI
NME/NM23 family member 8; Belongs to the NDK family.
  
 0.647
st3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family.
    
   0.590
fhl3
Four and a half LIM domains 3a.
    
 
 0.552
fkrp
Fukutin related protein.
   
  0.541
LOC100696561
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.521
LOC100694900
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.521
Ube2w
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
 0.503
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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