STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zfand2aZinc finger, AN1-type domain 2A. (275 aa)    
Predicted Functional Partners:
psmd6
Proteasome 26S subunit, non-ATPase 6.
   
   0.902
psmc6
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
   
   0.898
psmc5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
 
 0.787
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 
 0.784
uchl5
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.777
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.768
ublcp1
Ubiquitin-like domain containing CTD phosphatase 1.
    
 
 0.738
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
   0.736
psmd3
Proteasome 26S subunit, non-ATPase 3.
   
   0.715
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
   0.708
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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