STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phox2bPaired like homeobox 2Bb. (285 aa)    
Predicted Functional Partners:
phox2a
Paired like homeobox 2A.
   
 
 0.844
hand2
Heart and neural crest derivatives expressed 2.
   
 
 0.719
setdb1
SET domain bifurcated histone lysine methyltransferase 1b.
      
 0.701
th
Tyrosine hydroxylase.
   
  
 0.696
LOC100702996
Tyrosine hydroxylase 2.
   
  
 0.696
ENSONIP00000072738
Endothelin-3 isoform X1.
      
 0.642
sox10
SRY-box transcription factor 10.
      
 0.626
GPR68
G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family.
      
 0.625
gpr4
G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family.
      
 0.625
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.619
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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