STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC1006898961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)    
Predicted Functional Partners:
LOC100697949
Uncharacterized protein.
    
 0.924
LOC100711838
Guanine nucleotide-binding protein subunit alpha-14 isoform X1.
    
 0.924
DGKQ
Diacylglycerol kinase.
     
 0.911
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
 0.905
LOC100692028
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
 0.905
LOC100706143
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.905
LOC100706405
Uncharacterized protein.
    
 0.905
LOC100697855
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.905
Itpr3
Inositol 1,4,5-trisphosphate receptor, type 3.
   
 0.901
I3KBJ3_ORENI
Inositol 1,4,5-trisphosphate receptor, type 2.
   
 0.901
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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