pmvk protein (Oreochromis niloticus) - STRING interaction network

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Score

pmvk

Phosphomevalonate kinase. (200 aa)

Predicted Functional Partners:

Mvk

0.991

mvd

0.986

fdps

0.864

idi1

0.832

LOC100697646

0.805

LOC100712075

0.796

acy1

0.740

Sqle

0.724

rusc1

0.715

pdia6

0.711

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100697646	LOC100712075	ENSONIP00000049566	ENSONIP00000040815	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.999
LOC100697646	Mvk	ENSONIP00000049566	ENSONIP00000016956	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.992
LOC100697646	Sqle	ENSONIP00000049566	ENSONIP00000000207	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Squalene epoxidase a.	0.975
LOC100697646	acy1	ENSONIP00000049566	ENSONIP00000034569	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Aminoacylase 1.	0.443
LOC100697646	fdps	ENSONIP00000049566	ENSONIP00000068782	3-hydroxy-3-methylglutaryl coenzyme A reductase.	RUN and SH3 domain containing 1; Belongs to the FPP/GGPP synthase family.	0.914
LOC100697646	idi1	ENSONIP00000049566	ENSONIP00000049834	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Isopentenyl-diphosphate delta isomerase 1.	0.820
LOC100697646	mvd	ENSONIP00000049566	ENSONIP00000042568	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.820
LOC100697646	pmvk	ENSONIP00000049566	ENSONIP00000001771	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Phosphomevalonate kinase.	0.805
LOC100697646	rusc1	ENSONIP00000049566	ENSONIP00000030399	3-hydroxy-3-methylglutaryl coenzyme A reductase.	RUN and SH3 domain containing 1.	0.693
LOC100712075	LOC100697646	ENSONIP00000040815	ENSONIP00000049566	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.999
LOC100712075	Mvk	ENSONIP00000040815	ENSONIP00000016956	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.934
LOC100712075	Sqle	ENSONIP00000040815	ENSONIP00000000207	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Squalene epoxidase a.	0.977
LOC100712075	acy1	ENSONIP00000040815	ENSONIP00000034569	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Aminoacylase 1.	0.569
LOC100712075	fdps	ENSONIP00000040815	ENSONIP00000068782	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	RUN and SH3 domain containing 1; Belongs to the FPP/GGPP synthase family.	0.993
LOC100712075	idi1	ENSONIP00000040815	ENSONIP00000049834	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Isopentenyl-diphosphate delta isomerase 1.	0.978
LOC100712075	mvd	ENSONIP00000040815	ENSONIP00000042568	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.930
LOC100712075	pmvk	ENSONIP00000040815	ENSONIP00000001771	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Phosphomevalonate kinase.	0.796
LOC100712075	rusc1	ENSONIP00000040815	ENSONIP00000030399	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	RUN and SH3 domain containing 1.	0.855
Mvk	LOC100697646	ENSONIP00000016956	ENSONIP00000049566	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.992
Mvk	LOC100712075	ENSONIP00000016956	ENSONIP00000040815	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.934