Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD50Ankyrin repeat domain 50. (1426 aa)    
Predicted Functional Partners:
arl9
ADP-ribosylation factor-like 9.
    
 0.653
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.653
ppp6c
Serine/threonine-protein phosphatase.
    
 0.629
LOC100701794
Serine/threonine-protein phosphatase.
    
 0.629
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.592
SPATA5
Spermatogenesis associated 5.
    
 0.589
adad1
Adenosine deaminase domain containing 1 (testis-specific).
      
 0.575
bbs12
Bardet-Biedl syndrome 12.
      
 0.529
ppp6r3
Protein phosphatase 6, regulatory subunit 3.
    
 0.526
LOC100707632
Protein phosphatase 6, regulatory subunit 2a.
    
 0.526
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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