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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD50Ankyrin repeat domain 50. (1426 aa)    
Predicted Functional Partners:
ppp6c
Serine/threonine-protein phosphatase.
    
 0.567
LOC100701794
Serine/threonine-protein phosphatase.
    
 0.567
ppp6r3
Protein phosphatase 6, regulatory subunit 3.
    
 0.538
LOC100707632
Protein phosphatase 6, regulatory subunit 2a.
    
 0.538
LOC100707429
Protein phosphatase 6, regulatory subunit 2b.
    
 0.538
arl9
ADP-ribosylation factor-like 9.
    
 0.511
SPATA5
Spermatogenesis associated 5.
    
 0.507
ift81
Intraflagellar transport 81 homolog.
    
 0.500
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.483
I3KF91_ORENI
Intraflagellar transport 88 homolog.
    
 0.457
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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