Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prune1Prune exopolyphosphatase. (421 aa)    
Predicted Functional Partners:
I3KCA0_ORENI
CRAL-TRIO domain-containing protein.
 
   
 0.982
hddc3
HD domain containing 3.
     
 0.931
LOC100697171
Prune homolog 2 with BCH domain.
 
   
 0.929
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 
 0.846
LOC100709006
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 
 0.846
LOC100694962
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 
 0.846
utp20
UTP20 small subunit processome component.
      
 0.686
Ppp1r11
Protein phosphatase 1, regulatory (inhibitor) subunit 11.
      
 0.648
gmppb
GDP-mannose pyrophosphorylase B.
   
   0.632
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component.
      
 0.628
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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