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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
epas1Endothelial PAS domain protein 1b. (879 aa)    
Predicted Functional Partners:
ubxn7
UBX domain protein 7.
    
 0.956
vhl
Von Hippel-Lindau tumor suppressor.
    
 0.923
egln1
Egl-9 family hypoxia-inducible factor 1a.
    
 0.895
LOC100708914
Aryl hydrocarbon receptor nuclear translocator.
   
0.870
Arnt2
Aryl-hydrocarbon receptor nuclear translocator 2.
   
0.870
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.866
hif1an
Hypoxia inducible factor 1 alpha subunit inhibitor.
    
 0.852
cul2
Cullin 2; Belongs to the cullin family.
    
 0.820
LOC100691117
Egl-9 family hypoxia-inducible factor 2.
    
 0.813
ENSONIP00000049468
Egl-9 family hypoxia-inducible factor 3.
    
 0.813
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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