Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
epas1Endothelial PAS domain protein 1b. (879 aa)    
Predicted Functional Partners:
vhl
Von Hippel-Lindau tumor suppressor.
    
 0.970
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.953
cul2
Cullin 2; Belongs to the cullin family.
    
 0.947
egln1
Egl-9 family hypoxia-inducible factor 1a.
    
 0.914
hif1a
Hypoxia inducible factor 1 alpha variant X2.
     
  0.908
LOC100708832
Hypoxia inducible factor 1 subunit alpha, like.
     
  0.908
hif1an
Hypoxia inducible factor 1 alpha subunit inhibitor.
    
 0.907
LOC100708914
Aryl hydrocarbon receptor nuclear translocator.
   
 0.890
Arnt2
Aryl-hydrocarbon receptor nuclear translocator 2.
   
 0.890
I3JU14_ORENI
Elongin B.
    
 0.873
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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