Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wdr73WD repeat domain 73. (384 aa)    
Predicted Functional Partners:
I3JV04_ORENI
Translocase of outer mitochondrial membrane 20.
   
 0.932
arid4a
AT rich interactive domain 4A (RBP1-like).
   
 0.932
hat1
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
   
 0.895
ENSONIP00000079948
Uncharacterized protein LOC109194435 isoform X1.
   
 0.892
eed
Embryonic ectoderm development.
   
 0.888
lin52
Protein lin-52 homolog.
   
 0.858
wdr4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
  
 0.834
lin54
Lin-54 DREAM MuvB core complex component.
   
 0.825
suz12
SUZ12 polycomb repressive complex 2 subunit b.
   
 0.825
LOC100701898
VEFS-Box domain-containing protein.
   
 0.825
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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