Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100705545Protein S100; Belongs to the S-100 family. (92 aa)    
Predicted Functional Partners:
I3KUM9_ORENI
Protein S100; Belongs to the S-100 family.
   
 0.722
LOC100696284
Protein S100; Belongs to the S-100 family.
   
 0.705
s100a14
S_100 domain-containing protein; Belongs to the S-100 family.
     
 0.594
LOC100709534
S100 calcium binding protein U.
     
 0.561
LOC100690258
Annexin.
   
 0.541
anxa1
Annexin.
   
 0.541
ANXA2
Annexin.
   
 0.541
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
  0.537
I3JGD7_ORENI
Protein S100; Belongs to the S-100 family.
     
  0.479
LOC100709804
Protein S100; Belongs to the S-100 family.
     
  0.479
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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