Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)    
Predicted Functional Partners:
I3KMX6_ORENI
IK cytokine.
   
 0.994
mfap1
Microfibril associated protein 1.
   
 0.989
I3KN33_ORENI
Zinc finger, matrin-type 2.
    
 0.938
Wbp4
Uncharacterized protein.
    
 0.918
cd2bp2
CD2 (cytoplasmic tail) binding protein 2.
    
   0.915
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.904
Wbp11
WW domain binding protein 11.
    
 0.893
sf3b3
Splicing factor 3b, subunit 3.
   
 
 0.888
txnl4a
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
    
 0.887
UBL5
Ubiquitin like 5.
    
 0.878
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (38%) [HD]