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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU1SMU1 DNA replication regulator and spliceosomal factor. (513 aa)    
Predicted Functional Partners:
I3KMX6_ORENI
IK cytokine.
   
 0.980
mfap1
Microfibril associated protein 1.
   
 0.967
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
    
 0.911
I3KN33_ORENI
Zinc finger, matrin-type 2.
    
 0.908
prpf38a
Pre-mRNA processing factor 38A.
   
 0.898
prpf8
Pre-mRNA processing factor 8.
    
 
 0.879
Wbp4
Uncharacterized protein.
    
 0.864
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 
 0.861
UBL5
Ubiquitin like 5.
    
 0.843
lsm4
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 
 0.843
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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