STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyk2Tyrosine-protein kinase. (1174 aa)    
Predicted Functional Partners:
stat1
Signal transducer and activator of transcription.
   
 0.994
LOC100701534
Signal transducer and activator of transcription.
   
 0.989
LOC100704348
Signal transducer and activator of transcription.
   
 0.977
stat4
Signal transducer and activator of transcription.
   
 0.974
stat3
Signal transducer and activator of transcription.
   
 0.972
socs3
Suppressor of cytokine signaling 3.
   
 0.968
LOC100704232
Uncharacterized protein.
   
 0.967
ifngr2-1
Fibronectin type-III domain-containing protein.
    
 0.949
LOC100690945
Signal transducer and activator of transcription.
   
 0.941
LOC100692331
Signal transducer and activator of transcription.
   
 0.941
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.