Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tgfbiTransforming growth factor, beta-induced. (677 aa)    
Predicted Functional Partners:
lum
Lumican.
   
  
 0.594
ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    
 0.586
ndufs2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
    
 
 0.578
I3KEZ4_ORENI
Collagen, type VI, alpha 1.
   
  
 0.575
cemip2
Cell migration inducing hyaluronidase 2.
      
 0.551
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
   
 
 0.545
prrx1
Paired related homeobox 1a.
   
  
 0.512
ggcx
Gamma-glutamyl carboxylase.
   
  
 0.494
atoh8
Protein atonal homolog 8 isoform X1.
      
 0.469
fbln5
Fibulin 5.
   
  
 0.468
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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