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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Setd4SET domain containing 4. (456 aa)    
Predicted Functional Partners:
klhl23
Kelch-like family member 23.
      
 0.740
kiaa1958
Uncharacterized protein KIAA1958 homolog.
      
 0.631
mindy1
MINDY lysine 48 deubiquitinase 1.
    
 0.622
mmaa
Metabolism of cobalamin associated A.
    
 0.622
mindy2
Ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform X1.
    
 0.622
setd6
N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
    
 
 0.615
PRDM15
PR/SET domain 15.
    
 0.608
gamt
Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
   
  
 0.597
Rrnad1
Ribosomal RNA adenine dimethylase domain containing 1.
   
  
 0.593
mettl18
Methyltransferase like 18.
   
  
 0.590
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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