Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100706781Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1106 aa)    
Predicted Functional Partners:
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 0.997
Pik3r6
Phosphoinositide-3-kinase regulatory subunit 6.
    
 0.985
LOC100690007
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.980
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
  
0.965
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
  
0.963
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
0.961
LOC102078679
Phosphoinositide-3-kinase, regulatory subunit 6b.
    
  0.960
pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
  
  
 
0.960
LOC100707971
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.957
LOC100702193
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.957
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.