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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100694803Ras homolog family member Cb. (193 aa)    
Predicted Functional Partners:
Rock1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.974
rock2
Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 0.974
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
   
 0.965
arhgef12
Rho guanine nucleotide exchange factor (GEF) 12a.
   
 0.965
arhgap5
Rho GTPase activating protein 5.
    
 0.963
LOC100710886
Rho GTPase activating protein 35b.
    
 0.963
arhgap35
Uncharacterized protein.
    
 0.963
ARHGEF2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
   
 0.959
LOC100704015
Rho guanine nucleotide exchange factor (GEF) 1a.
   
 0.959
LOC100701417
Rho-associated, coiled-coil containing protein kinase 2b; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 0.958
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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