Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gnb4Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (359 aa)    
Predicted Functional Partners:
drd2
Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family.
    
  0.962
calcr
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
  0.962
drd3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
  0.962
gper1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.959
LOC100699280
Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.
    
 0.954
LOC100695984
Melanocortin 4 receptor.
    
 0.953
LOC100692941
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
  0.952
LOC100712192
Melanin-concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
  0.952
oprd1
Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.951
LOC100712332
Opioid receptor, mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.951
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.