Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ube2j1Ubiquitin-conjugating enzyme E2, J1. (317 aa)    
Predicted Functional Partners:
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.986
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.967
Prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
  0.957
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 0.935
LOC102081483
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.900
aup1
AUP1 lipid droplet regulating VLDL assembly factor.
   
 
 0.894
amfr
Autocrine motility factor receptor b.
    
 
 0.870
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
    
 
 0.870
c1qtnf12
C1q and TNF related 12.
    
 0.854
Ube2w
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
 0.850
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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