Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
I3IZW4_ORENICoiled-coil domain containing 181. (512 aa)    
Predicted Functional Partners:
ppp1r32
Protein phosphatase 1, regulatory subunit 32.
      
 0.895
mrpl30
Mitochondrial ribosomal protein L30.
      
 0.858
rassf3
Ras association domain family member 3.
      
 0.728
Cfap100
Cilia and flagella associated protein 100.
      
 0.699
ccdc9
Coiled-coil domain containing 9.
      
 0.694
ccdc113
DUF4201 domain-containing protein.
      
 0.690
cfap58
Cilia and flagella associated protein 58.
      
 0.681
I3KBQ4_ORENI
Uncharacterized protein.
      
 0.659
wdr35
WD repeat-containing protein 35.
      
 0.639
I3K9B0_ORENI
GFA domain-containing protein.
      
 0.628
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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