Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cpoxCoproporphyrinogen oxidase. (455 aa)    
Predicted Functional Partners:
urod
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.995
Ppox
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.994
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.966
uros
Uroporphyrinogen-III synthase.
     
 0.924
ENDOV
Endonuclease V.
  
 0.924
twnk
Twinkle mtDNA helicase.
    
   0.913
hmbs
Hydroxymethylbilane synthase a.
  
 
 0.847
alas1
5-aminolevulinate synthase.
  
  
 0.804
cct6a
Chaperonin containing TCP1, subunit 6A (zeta 1).
   
 
 0.790
SKIDA1
SKI/DACH domain containing 1.
    
   0.784
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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