I3IZY9_ORENI protein (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

I3IZY9_ORENI

ALK and LTK ligand 1. (156 aa)

Predicted Functional Partners:

LOC100690943

0.803

alk

0.803

I3IU13_ORENI

0.624

LOC100701740

0.555

mst1r

0.555

met

0.555

henmt1

0.550

sh3yl1

0.523

Plcg2

0.512

plcg1

0.512

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3IU13_ORENI	I3IZY9_ORENI	ENSONIP00000000103	ENSONIP00000002179	Pleiotrophin.	ALK and LTK ligand 1.	0.624
I3IU13_ORENI	LOC100690943	ENSONIP00000000103	ENSONIP00000025316	Pleiotrophin.	Tyrosine-protein kinase receptor.	0.797
I3IU13_ORENI	LOC100701740	ENSONIP00000000103	ENSONIP00000005149	Pleiotrophin.	Macrophage stimulating 1 receptor a.	0.648
I3IU13_ORENI	Plcg2	ENSONIP00000000103	ENSONIP00000013486	Pleiotrophin.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.544
I3IU13_ORENI	alk	ENSONIP00000000103	ENSONIP00000070280	Pleiotrophin.	Tyrosine-protein kinase receptor.	0.797
I3IU13_ORENI	met	ENSONIP00000000103	ENSONIP00000080477	Pleiotrophin.	MET proto-oncogene, receptor tyrosine kinase.	0.648
I3IU13_ORENI	mst1r	ENSONIP00000000103	ENSONIP00000025557	Pleiotrophin.	Macrophage stimulating 1 receptor b.	0.648
I3IU13_ORENI	plcg1	ENSONIP00000000103	ENSONIP00000021988	Pleiotrophin.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.544
I3IZY9_ORENI	I3IU13_ORENI	ENSONIP00000002179	ENSONIP00000000103	ALK and LTK ligand 1.	Pleiotrophin.	0.624
I3IZY9_ORENI	LOC100690943	ENSONIP00000002179	ENSONIP00000025316	ALK and LTK ligand 1.	Tyrosine-protein kinase receptor.	0.803
I3IZY9_ORENI	LOC100701740	ENSONIP00000002179	ENSONIP00000005149	ALK and LTK ligand 1.	Macrophage stimulating 1 receptor a.	0.555
I3IZY9_ORENI	Plcg2	ENSONIP00000002179	ENSONIP00000013486	ALK and LTK ligand 1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.512
I3IZY9_ORENI	alk	ENSONIP00000002179	ENSONIP00000070280	ALK and LTK ligand 1.	Tyrosine-protein kinase receptor.	0.803
I3IZY9_ORENI	henmt1	ENSONIP00000002179	ENSONIP00000010518	ALK and LTK ligand 1.	HEN methyltransferase 1.	0.550
I3IZY9_ORENI	met	ENSONIP00000002179	ENSONIP00000080477	ALK and LTK ligand 1.	MET proto-oncogene, receptor tyrosine kinase.	0.555
I3IZY9_ORENI	mst1r	ENSONIP00000002179	ENSONIP00000025557	ALK and LTK ligand 1.	Macrophage stimulating 1 receptor b.	0.555
I3IZY9_ORENI	plcg1	ENSONIP00000002179	ENSONIP00000021988	ALK and LTK ligand 1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.512
I3IZY9_ORENI	sh3yl1	ENSONIP00000002179	ENSONIP00000023609	ALK and LTK ligand 1.	SH3 and SYLF domain containing 1.	0.523
LOC100690943	I3IU13_ORENI	ENSONIP00000025316	ENSONIP00000000103	Tyrosine-protein kinase receptor.	Pleiotrophin.	0.797
LOC100690943	I3IZY9_ORENI	ENSONIP00000025316	ENSONIP00000002179	Tyrosine-protein kinase receptor.	ALK and LTK ligand 1.	0.803