Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
frmd8FERM domain containing 8. (471 aa)    
Predicted Functional Partners:
RHBDF2
Rhomboid 5 homolog 2.
     
 0.861
LOC100703856
Rhomboid 5 homolog 1b (Drosophila).
     
 0.861
rhbdf1
Rhomboid 5 homolog 1a (Drosophila).
     
 0.861
itgb1bp1
Integrin beta 1 binding protein 1.
    
 
 0.757
znrd2
Zinc ribbon domain containing 2.
      
 0.712
LOC100705437
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
      
 0.676
ccm2
CCM2 scaffold protein.
    
  0.660
SLC25A45
Solute carrier family 25 member 45; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.628
I3KDG2_ORENI
U-box domain containing 5.
   
  
 0.627
I3JA42_ORENI
Syntaxin 6; Belongs to the syntaxin family.
      
 0.624
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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