Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3J007_ORENIRing finger protein 220b. (319 aa)    
Predicted Functional Partners:
zc4h2
Zinc finger, C4H2 domain containing.
    
 
 0.913
LOC100692499
Uncharacterized protein.
      
 0.673
usp7
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
    
 
 0.612
RPL27A
Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.
    
   0.579
fbxo3
F-box protein 3.
      
 0.529
ENSONIP00000047919
Ubiquitin B.
    
 0.516
sin3a
SIN3 transcription regulator family member Aa.
    
 0.515
sin3b
SIN3 transcription regulator family member B.
    
 0.515
LOC100694434
SIN3 transcription regulator family member Ab.
    
 0.515
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
    
   0.504
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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